The Way We KIll Houseflies Now

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Obama Lauds Higher US Car Sales (Voice Of America)

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New U.S. policy seeks to end legal battle over eagle feathers ? CNN ...

By Terry Frieden, CNN Justice Producer

Washington (CNN) ? The Justice Department sought on Friday to strike a delicate balance between the use of bald eagle feathers by Native American tribes and federal protection of the nation's symbolic bird.

A new government policy would allow tribes to "possess, use, wear or carry" federally protected birds or bird feathers. However, they could not buy or sell the feathers or other bird parts.

The eagle feathers have been of great religious and cultural significance to many tribes. Bald eagles are dark brown with a white head and tail.

The bald eagle has been the national symbol since 1782.

"The Department of Justice is committed to striking the right balance in enforcing our nation's wildlife laws by respecting the cultural and religious practices of federally recognized Indian tribes," said Attorney General Eric Holder in announcing the policy.

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Holder said the step was needed to address concerns of tribal members unsure of whether they could be prosecuted for their religious and cultural practices involving eagle feathers.

Justice and Interior Department officials met several times with tribal leaders during the past year to try to resolve the issue, which has ended up in federal courts.

The bald eagle became an endangered species some 70 years ago and was threatened with extinction.

Congress passed a law that prohibited killing or possessing the majestic bird. That law and tough enforcement succeeded, and by 2007 the bird was removed from the endangered list. It remains protected, however, by laws enforced by the Fish and Wildlife Service.

CNN?s Belief Blog: The faith angles behind the biggest stories

Robert Holden, deputy director of the National Congress of American Indians, described to CNN the historic fascination with the eagle.

"It flies higher than any other creature. It sees many things. It's closer to the Creator," Holden said.

Source: http://religion.blogs.cnn.com/2012/10/12/new-u-s-policy-seeks-to-end-legal-battle-over-eagle-feathers/

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After beating Birds, Yankees look to tame Tigers

Baltimore Orioles' Matt Wieters, top, heads off the field as the New York Yankees celebrate their victory in the American League division baseball series on Friday, Oct. 12, 2012, in New York. The Yankees won the game 3-1 and advanced to the AL championship. (AP Photo/Peter Morgan)

Baltimore Orioles' Matt Wieters, top, heads off the field as the New York Yankees celebrate their victory in the American League division baseball series on Friday, Oct. 12, 2012, in New York. The Yankees won the game 3-1 and advanced to the AL championship. (AP Photo/Peter Morgan)

New York Yankees starting pitcher CC Sabathia waves to the fans as he leaves the field after Game 5 of the American League division baseball series against the Baltimore Orioles, Friday, Oct. 12, 2012, in New York. The Yankees won the game 3-1 and advanced to the AL championship. (AP Photo/Kathy Willens)

New York Yankees' CC Sabathia (52) reacts after Game 5 of the American League division baseball series against the Baltimore Orioles, Friday, Oct. 12, 2012, in New York. The Yankees won the game 3-1 and advanced to the AL championship. (AP Photo/Kathy Willens)

New York Yankees' pitcher CC Sabathia embraces catcher Russell Martin after winning Game 5 of the American League division baseball series against the Baltimore Orioles, Friday, Oct. 12, 2012, in New York. The Yankees won the game 3-1 and advanced to the AL championship. Yankees' Eric Chavez approached at right. (AP Photo/Peter Morgan)

New York Yankees starting pitcher CC Sabathia is doused by teammate Ivan Nova, right, as they celebrate in the clubhouse after Game 5 of the American League division baseball series against the Baltimore Orioles, Friday, Oct. 12, 2012, in New York. The Yankees won the game 3-1 and advanced to the AL championship. (AP Photo/Kathy Willens)

NEW YORK (AP) ? CC Sabathia boosted the New York Yankees past the Baltimore Orioles, ending a spellbinding six-week drama that drove and drained both teams.

New York advanced to an AL championship series matchup with Detroit, beating Baltimore 3-1 in Game 5 of their AL division series on Friday behind Sabathia's four-hitter.

Andy Pettitte, the career postseason leader with 19 wins, starts Game 1 for the Yankees on Saturday night with a rested bullpen behind him, opposed by Doug Fister. It's a rematch of last year's division series won by the Tigers in five games and provides a platform for Detroit's Miguel Cabrera, baseball's first Triple Crown winner in 45 years.

"I don't know if you can shut him down, but try to keep him from doing too much damage in the series, and that's key to us winning," Pettitte said.

Yankees manager Joe Girardi faces another big decision. After benching slumping Alex Rodriguez for Game 5 against the Orioles, will he insert him back at third base against a Detroit team with four right-handers in its starting rotation?

To get back to the ALCS for the first time in two years, the Yankees had to shake off Baltimore. The teams were separated by no more than a game from Sept. 3-24, the longest September stretch that tight between first- and second-place clubs since the 19th century.

The Yankees had some help from the right field umpire, just as they did against the Orioles in the 1996 ALCS ? hello, Jeffrey Maier.

With New York ahead 1-0 in the sixth, Nate McLouth's drive down the right-field line on a 3-1 pitch was called foul by the slimmest of margins.

Fieldin Culbreth demonstrably waved foul with both arms. Orioles manager Buck Showalter jogged onto the field to ask for a video review, and four umpires went down a tunnel on the third-base side to examine the images on a screen near their dressing room. When they ran back onto the field about two minutes later, they didn't make any signal ? meaning the original call stood. McLouth struck out on the next pitch, ending the inning.

"I saw it go to the right of the pole," Culbreth said. "There is netting there and it didn't touch the netting. It did not change direction," he added, indicating he did not think the ball grazed the pole.

Added crew chief Brian Gorman: "We saw the same thing on the replay. There was no evidence to overturn the decision."

McLouth wondered what the umps would decide.

"It started off fair and it was just hooking a little bit. I thought it was foul just in game speed," McLouth said. "A couple of people mentioned it might've ticked the pole, but he was way closer than I was and I was satisfied after they went down and looked at the replay that it was foul."

Steven Ellis, a fan from the Broad Channel section of Queens, caught the ball with his Yankee cap in the second deck.

"It was foul all the way, never hit the pole," he said.

Back in 1996, the 12-year-old Maier reached over the wall above right fielder Tony Tarasco and deflected Derek Jeter's fly ball. Umpire Richie Garcia called it a home run, which tied the score 4-all in the eighth inning, and the Yankees went on to win in the 11th.

"Just watching at home, I promise," Maier texted to The Associated Press after this play.

Sabathia went on to defeat the Orioles for the second time in six days, Raul Ibanez hit a go-ahead single in the fifth off Jason Hammel after former Baltimore high school star Mark Teixeira singled and swiped second in a rare steal. Diving second baseman Robert Andino just missed gloving Ibanez's hit.

Ichiro Suzuki added an RBI double off the right-center field wall in the sixth. Curtis Granderson boosted the lead to 3-0 with a second-deck solo homer against Troy Patton in the seventh.

Sabathia, who improved to 4-0 in his last eight postseason starts, didn't allow an extra-base hit. He struck out nine, walked two and matched his season high of 121 pitches.

"He didn't pitch all five, but it certainly felt like it, didn't it?" Showalter said.

Sabathia took a one-hit shutout into the eighth but allowed Matt Wieters' leadoff single and Manny Machado's walk. Mark Reynolds struck out, and Lew Ford ? starting at DH in place of Jim Thome ? hit an RBI single.

Andino hit a bouncer to the third-base side that Sabathia gloved, but Eric Chavez left third uncovered and Sabathia's throw to second was late, leaving the bases loaded. With David Robertson warming up in the New York bullpen, McLouth struck out on a changeup and Sabathia escaped when J.J. Hardy hit a slow three-hopper to shortstop that Jeter, playing on a sore left ankle, charged and gloved elegantly before throwing to first just in time.

Sabathia pitched a 1-2-3 ninth, finishing a 121-pitch effort as Wieters hit a comebacker. The Yankees ran out of their dugout to celebrate on the third-base side of the mound and the Orioles walked off slowly and somberly.

"It's been about as much fun as I have had in the big leagues watching how they play the game every day, the standard they held themselves to and the way they raised the bar in Baltimore with each other," said Showalter, who has not reached the LCS in 14 major league seasons.

New York won for the 12th time in 23 meetings between the teams in a matchup so close the Yankees outscored the Orioles 106-102. The teams were within one run of each other at the end of 46 of 52 innings in the division series. New York totaled just 16 runs in the five games and Baltimore 10, ending a dynamic six-week struggle. After 10 different nights in September, the rivals were tied for first.

"They are a very good club and they are a very resilient club," Girardi said. "People thought they were going to go away, they never went away."

NOTES: The crowd of 47,081 was the smallest in 18 postseason games at new Yankee Stadium, which opened in 2009. ... New York is 11-3 in the ALCS. ... The 26 runs were the fewest in a five-game postseason series since St. Louis (12) and Arizona (10) combined for 22 runs in the 2001 NLDS.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2012-10-13-BBA-ALDS-Orioles-Yankees-Folo/id-c0254eee9d224840890feaa839181fc6

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A Culture of Excess ? The Well-Rounded Home

Hi there! I'm glad you stopped by for a visit. Be sure to get on the newsletter list for regular updates and freebies.

Have you ever thought about how much stuff you and your family have? It?s been on my mind a lot lately. Our American culture is one of excess.

Yet, for all that we have, we?re probably still no more contented, at peace, happy, successful or loved than if we lived a more simple life. (Plus, at least in my house, it often results in having more stuff to clean up and maintain.) Here are a few examples of excess we live with:

• Calendar appointments
• Long to do lists
• Unused apps on phones
• Unread books
• DVR recordings
• Hundreds of television channels
• Clothes we?re saving for our skinny self or for when they come back in style
• Nice dishes that never get eaten on
• Craft supplies
• Toys
• Gadgets
• Computer files
• Digital photos
• Superficial friendships on Facebook, Twitter and other social media outlets
• Unhealthy calories consumed
• DVDs we never watch
• CDs we?ve long forgotten we own

I?m working on simplifying things. It?s ?a long process. I secretly envy people who write about moving to a foreign country or small town with two bags of possessions.?Already, I?ve spent two days going through my side of the closet, and it?s still a mess. I get overwhelmed by all the stuff and want to quit.

Part of the difficulty is the letting go. Even with things that have sat unused for years, it?s hard convincing myself that I don?t really need something or really won?t use it; but I?m slowly getting there. My plan is to work my way through each room of our house.?This 31 Days of Margin series couldn?t have been timed any better. I?m learning a lot about creating space and getting rid of excess.

What about you?Do you ever feel like you have too much in your life? What things are hardest for you to give up?

p.s. I'm catching up on the Love Tune-Up series this weekend. It's been a full week of running for a 5K I'm doing this weekend and our Church's annual conference. I also had two guests posts this week: Stay Sane While Blogging and?101 Days of Christmas: Peppermint Hand Scrub. Please stop by and check them out.

Source: http://wellroundedhome.com/2012/10/12/culture-of-excess/

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Blame Baker for Reds' collapse

Scott Rolen just struck out to end Game 5 of the NLDS. The Giants win 6-4 and now they?ll go on to face the winner of the Nats-Cardinals series.

This wasn?t all on Dusty Baker. ?It wasn?t Dusty Baker who was beat around like nobody?s business in the fifth inning. That was Mat Latos, who suffered a total meltdown after not getting a couple of close calls, resulting in a grand slam by Buster Posey. ?It likewise wasn?t Dusty Baker who ended a would-be Reds rally in the eighth. That had an awful lot to do with the Giants leather, first with Brandon Crawford making a diving stop at short and then Angel Pagan doing the same in center. ?Indeed, the Reds stranded all kinds of runners from the fifth inning on. Sometimes, stuff just happens. You don?t get the bounce and you don?t get the clutch hit.

But Baker didn?t do his team any favors in Games 3, 4 or 5, and a good argument can be made that Baker cost them the series because of it.

On Tuesday it was Scott Rolen?s error in extra innings which opened the door for the Giants victory. Given how much Rolen struggled down the stretch, it?s an open question as to why he was playing at all. ?Yesterday Baker left starting pitcher Mike Leake in for too long, and he got rocked, forcing the Reds to play come-from-behind baseball almost the whole game. ?Then today in the sixth, with two on, nobody out and Ryan Hanigan working the count full,?Baker ran them out of the inning with an ill-advised hit and run ? or run and hit or a steal or whatever it was ? which turned into a momentum-sapping double play.

Any loss is a team effort. But Baker?s decisions put the Reds in disadvantageous situations time and time again against the Giants. ?In a short series, that can be death. ?It certainly was here.

Source: http://hardballtalk.nbcsports.com/2012/10/11/the-reds-are-dead-and-dusty-bakers-fingerprints-are-all-over-the-murder-weapon/related/

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Learn Approaches for Music Distribution

For several years self-employed Music Distribution had been each challenging as well as costly to complete. As an self-employed artist you had to handle muscle size replication of the actual physical photo album as well as figuring out a way to get the photo album in to log shops. This particular made self-employed Music Distribution nearly impossible for many performers. Financing in isolation had been usually a large sufficient obstacle to stop performers from getting their own photo album out from the studio as well as on to the store's corner.

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Do some looking into on-line with regard to probable self-employed Music Distribution corporations. This is when you need to release your own photo album, on-line. Allow the log labeling deal with muscle size syndication regarding actual physical C/D's. As an self-employed artist you will be able towards your songs out to a lot more people for any significant less money doing it on-line.

Such as everything in every area of your life, there is a charge involved with on-line self-employed Music Distribution. Discover a business that just costs a small percentage for each down load. This way an individual pay lots of money in advance. Instead the syndication business as well as a person will get paid only when your own songs is actually purchased as well as down loaded. The small sum of money you might include the syndication service is actually worthwhile.

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Source: http://www.artipot.com/articles/1400248/learn-approaches-for-music-distribution.htm

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Featured: Google's Chief Legal Officer Weighs In on Software Patents

Google legal officer David Drummond agrees that the U.S. patent system is going overboard right now with all of its lawsuits, but he?ll be the first to admit it?s a complicated situation.

Google, and ? in extension ? all of its related Android manufacturers, are seemingly constantly dealing with major legal issues with Apple and Microsoft. Despite the constant threats and countersuits between the companies, Mr. Drummond does not believe that any of them want to keep dealing with it all. ?It doesn?t take much digging to find statements from Apple, Microsoft, all lamenting the fact that we have this patent litigation. These are not companies that say we?re all about patents and wake up in the morning wanting to think about patents.?

The problem, he says, lies in the fact that it?s too easy to get patents on software in the United States. ?There are places in the world where you can?t get a software patent, or at least it?s harder, like Europe. We think that?s probably the better way to go.?

Unfortunately for the current state of software of innovation, the U.S. patent system has very specific reasons for its rules and regulations. Making a big shift now could seriously threaten pharmaceutical and biotech industries, both of which depend heavily on patent protection in order to provide vastly profitable solutions.

?I think what we need to do is move past the one-size-fits-all and start thinking about software patents more specifically,? Drummond said. ?If you talk about software patents, I don?t think those other industries will feel as threatened.?

Drummond drew comparisons between mobile computing court battles of today and the lawsuits surrounding chipmakers in the late 80s and early 90s, but he drew a fine line between physical innovation on hardware and intellectual innovation in software.

?I would argue semiconductors fit the model for [patent] protection more than software does,? he said. ?We?re talking about algorithms here. In some ways, it?s math. I think you?d want to be more careful about giving monopoly protection than you might for some hardware ideas. I don?t think we should just say ?Well, this is the cycle we always go through.??

And if Google is saying that software patents shouldn?t be as strict, you know that?s a big deal. After all, Google has had a stranglehold on search for years now with their mysterious algorithms.

Source: Wall Street Journal
Image Source: China Law and Policy

Tags: Android legal, david drummond, featured, Google legal, patent battles, software patents

Category: androidheadlines.com

Source: http://androidheadlines.com/2012/10/featured-googles-chief-legal-officer-weighs-in-on-software-patents.html

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T-Mobile LG Optimus L9 hands-on

Entry level is the name of the game for the LG Optimus L9 on T-Mobile. We knew that, of course, from T-Mobile and LG's positioning of the Ice Cream Sandwich smartphone, as well as from the specs on paper. Let's recap:

• Android 4.0 (ICS)
• Dimensions: 5.19 x 2.69 x 0.36
• Weight: 4.41 oz
• 4.5-inch qHD Corning Gorilla Glass 2 Display (540 x 960)
• 1GB RAM
• 4GB built-in storage
• MicroSD storage expansion (up to 32GB)
• 1GHz dual-core processor
• 5-megapixel camera w/ LED flash
• 0.3-megapixel VGA front-facing camera
• 2,150mAh Battery
• Wi-Fi Connectivity: 802.11 b/g/n/a

Nothing the spec-conscious crowd will write home about, no? But here's the thing: It's a surprisingly solid entry-level device. You can't quite appreciate just how light it is until you grab it. 

In the hand, though, the L9's a ridiculously light device. It's decidedly plastic, but it's a soft plastic. (Kind of like a dry heat, I suppose.) The user interface seemed quick enough, though the device is loaded down in T-Mobile and LG applications. This is a buy-and-drive device, designed to be used out of the box, for folks who don't want to do a whole lot of customization.

The good news is that it's got a removable battery and microSD card. The power plant is respectable, but the four gigabytes of built-in storage most certainly isn't.

We've got a bevy of pics and video after the break.

read more

Source: http://feedproxy.google.com/~r/androidcentral/~3/u1bVDDP5XQU/story01.htm

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Obama: Romney trying 'to cloud' abortion stance (The Arizona Republic)

Share With Friends: | | Politics - Top Stories News, RSS Feeds and Widgets via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/254629338?client_source=feed&format=rss

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Deal of the Day: 46% off Seidio ACTIVE Case (with kickstand) for iPhone 5

Today Only: Buy the Seidio ACTIVE Case (with kickstand) for iPhone 5 and save $15.95!

The Seidio ACTIVE Case provides great shock and impact absorption while adding minimal bulk to your iPhone 5. This two-layer case features a compact and lightweight rubber polymer with a precisely positioned hard skeleton for added protection. Comes in black, blue, red, purple, white, green and features a retractable kickstand.

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Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/gOqBCAmqQ7w/story01.htm

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Dependable borrowers with only one credit score

By Erica?Sandberg

Opening Credits

Erica Sandberg is a prominent personal finance authority and author of "Expecting Money: The Essential Financial Plan for New and Growing Families." She writes "Opening Credits," a weekly reader Q&A column about issues for people who are new to credit, for CreditCards.com. Ask a question. 'Opening Credits' stories

Dear Opening Credits,
For 30 years prior to 2011, my wife and I paid off two mortgages though our local savings bank. Since that bank only reports to one credit bureau, our FICO score is low, even though we never missed a payment. Living in a new large city and trying to get a VA refinance, we are constantly frustrated with having a too-low FICO score (since the high and low are thrown out) and having an insufficient mortgage history with two of the credit bureaus. I have tried to talk to the two credit bureaus that were not reported to. They are deaf to this injustice, saying that the old savings bank we used would have to join their credit bureau for a report to be accepted. What do we do? --?Michael

Dear Michael,
Kudos to you for three decades of responsible borrowing and repaying! Now you're reaping the rewards with a credit report that shows your impressive history.

However, evidence of your wonderfulness is being reflected on just one of the reports, but it's still there and you can probably work around the other two.

First, know that creditors are not required by law to report to the consumer credit bureaus at all. It's their choice, and they may do so with one, two or all three of the reporting companies. Most financial institutions report to all three, but there is a cost involved, so if they want to save money, they can pare it down to a couple or none.

I've said it before and I'll say it again: This credit reporting business is fascinating! As a subscriber, a lender pays to report the monthly activity that you are making. The credit bureaus then take the data from all subscribers and compile it into files that they then resell to the subscribers -- and any other company or person that has a legitimate business need for it. Another source of revenue for them is you. Consumers may receive free reports once per year (at AnnualCreditReport.com) and when fraud is suspected, but if you want more you'll have to cough up a fee.?

Now, on to your question. What can you do about a bank that only reports to one bureau? Your FICO scores are looking rather strange because of it. After all, such scores are generated from the information on a credit report, so if only one has the mortgage payments on it and the others don't, you'll see radically different numbers among them.

I spoke with Sonya Smith-Valentine, founder of Financially Fierce and an attorney who specializes in banking and credit reporting issues, about your situation. Her suggestion is to forget appealing to the bureaus, because they just list what's given them. Instead, reach out to the president of the local savings bank you've been dealing with all these years and ask to communicate with someone high up in management. When you get that person on the line, explain your dilemma (being sure to emphasize how fantastic a customer you've been) and request that they add your account to the other two credit reporting bureaus. They may, and if they if they do, all your FICO scores will soon be about the same.

If that doesn't work, Smith-Valentine recommends that you look for a mortgage company that will do their own rescoring. You've got proof that you have repaid a couple of home loans, so ask them to include your satisfied mortgages in their own mathematical mix.

In the end, remember that all banks want is to lend money to people who have been great borrowers in the past, and who have an income that shows they have the capacity to repay future loans. If you've got those two qualities, you'll get the refinancing deal you're seeking.

See related: FICO's 5 factors: The components of a FICO credit score, 10 surefire steps to get errors off your credit reports

Erica Sandberg's articles and insight are featured in such publications as the Wall Street Journal, Pregnancy, Babytalk, Redbook, Bank Investment Consultant, Prosper.com, MSNMoney.com, and Smartmoney.com. An active television and radio commentator, Erica is the credit and money management expert for San Francisco?s KRON-TV, a frequent guest on Forbes Video Network, Fox Business News, Businessweek-TV, and all Bay Area networks. Prior to launching her own reporting and consulting business, she was affiliated with Consumer Credit Counseling Services of San Francisco where she counseled individuals, conducted educational workshops, and led the media relations department. Erica is a member of the Society of American Business Editors and Writers, and on the advisory committee for Project Money.

Send your question to Erica.

Published: October 10, 2012

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Source: http://www.creditcards.com/credit-card-news/payment-history-reporting-credit-bureaus-1377.php

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The Helix Nebula: Bigger in death than life

ScienceDaily (Oct. 4, 2012) ? A dying star is refusing to go quietly into the night, as seen in a combined infrared and ultraviolet view from NASA's Spitzer Space Telescope and the Galaxy Evolution Explorer (GALEX), which NASA has lent to the California Institute of Technology in Pasadena. In death, the star's dusty outer layers are unraveling into space, glowing from the intense ultraviolet radiation being pumped out by the hot stellar core.

This object, called the Helix nebula, lies 650 light-years away in the constellation of Aquarius. Also known by the catalog number NGC 7293, it is a typical example of a class of objects called planetary nebulae. Discovered in the 18th century, these cosmic works of art were erroneously named for their resemblance to gas-giant planets.

Planetary nebulae are actually the remains of stars that once looked a lot like our sun. These stars spend most of their lives turning hydrogen into helium in massive runaway nuclear fusion reactions in their cores. In fact, this process of fusion provides all the light and heat that we get from our sun. Our sun will blossom into a planetary nebula when it dies in about five billion years.

When the hydrogen fuel for the fusion reaction runs out, the star turns to helium for a fuel source, burning it into an even heavier mix of carbon, nitrogen and oxygen. Eventually, the helium will also be exhausted, and the star dies, puffing off its outer gaseous layers and leaving behind the tiny, hot, dense core, called a white dwarf. The white dwarf is about the size of Earth, but has a mass very close to that of the original star; in fact, a teaspoon of a white dwarf would weigh as much as a few elephants!

The intense ultraviolet radiation from the white dwarf heats up the expelled layers of gas, which shine brightly in the infrared. GALEX has picked out the ultraviolet light pouring out of this system, shown throughout the nebula in blue, while Spitzer has snagged the detailed infrared signature of the dust and gas in red, yellow and green. Where red Spitzer and blue GALEX data combine in the middle, the nebula appears pink. A portion of the extended field beyond the nebula, which was not observed by Spitzer, is from NASA's all-sky Wide-field Infrared Survey Explorer (WISE). The white dwarf star itself is a tiny white pinprick right at the center of the nebula.

More information about Spitzer is online at http://spitzer.caltech.edu and http://www.nasa.gov/spitzer . More information about GALEX is at http://www.galex.caltech.edu .

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The above story is reprinted from materials provided by NASA/Jet Propulsion Laboratory.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/F8xeUz9aFQY/121004121846.htm

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Graphene nanopores can be controlled: Less costly ways of sequencing DNA

ScienceDaily (Oct. 3, 2012) ? Engineers at The University of Texas at Dallas have used advanced techniques to make the material graphene small enough to read DNA.

Shrinking the size of a graphene pore to less than one nanometer -- small enough to thread a DNA strand -- opens the possibility of using graphene as a low-cost tool to sequence DNA.

"Sequencing DNA at a very cheap cost would enable scientists and doctors to better predict and diagnose disease, and also tailor a drug to an individual's genetic code," said Dr. Moon Kim, professor of materials science and engineering. He was senior author of an article depicted on the cover of the September print edition of Carbon.

The first reading, or sequencing, of human DNA by the international scientific research group known as the Human Genome Project cost about $2.7 billion. Engineers have been researching alternative nanomaterials materials that can thread DNA strands to reduce the cost to less than $1,000 per person.

Dr. Moon Kim, professor of materials science and engineering, was the senior author of the article.

It was demonstrated in 2004 that graphite could be changed into a sheet of bonded carbon atoms called graphene, which is believed to be the strongest material ever measured. Because graphene is thin and strong, researchers have searched for ways to control its pore size. They have not had much success. A nanoscale sensor made of graphene could be integrated with existing silicon-based electronics that are very advanced and yet cheap, to reduce costs.

In this study, Kim and his team manipulated the size of the nanopore by using an electron beam from an advanced electron microscope and in-situ heating up to 1200 degree Celsius temperature.

"This is the first time that the size of the graphene nanopore has been controlled, especially shrinking it," said Kim. "We used high temperature heating and electron beam simultaneously, one technique without the other doesn't work."

Now that researchers know the pore size can be controlled, the next step in their research will be to build a prototype device.

"If we could sequence DNA cheaply, the possibilities for disease prevention, diagnosis and treatment would be limitless," Kim said. "Controlling graphene puts us one step closer to making this happen."

Other UT Dallas researchers from the Erik Jonsson School of Engineering and Computer Science involved in this project are Dr. Ning Lu, research scientist in materials science and engineering; Dr. Jinguo Wang, associate EM Facility Director; and Dr. Herman Carlo Floresca, postdoctoral research fellow in materials science and engineering.

The study was funded by the Southwest Academy of Nanoelectronics, Air Force Office of Scientific Research and the World Class University Program.

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Journal Reference:

1. Ning Lu, Jinguo Wang, Herman C. Floresca, Moon J. Kim. In situ studies on the shrinkage and expansion of graphene nanopores under electron beam irradiation at temperatures in the range of 400?1200?C. Carbon, 2012; 50 (8): 2961 DOI: 10.1016/j.carbon.2012.02.078

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/Zy-Ggh8iKLA/121003141406.htm

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Cardinals clinch baseball's last postseason berth

St. Louis Cardinals' Matt Holliday is congratulated by manager Mike Matheny, left, and hitting coach Mark McGwire, right, after driving in a run with a sacrifice fly during the first inning of a baseball game against the Cincinnati Reds on Tuesday, Oct. 2, 2012, in St. Louis. (AP Photo/St. Louis Post-Dispatch, Chris Lee) EDWARDSVILLE INTELLIGENCER OUT; THE ALTON TELEGRAPH OUT.

St. Louis Cardinals' Matt Holliday is congratulated by manager Mike Matheny, left, and hitting coach Mark McGwire, right, after driving in a run with a sacrifice fly during the first inning of a baseball game against the Cincinnati Reds on Tuesday, Oct. 2, 2012, in St. Louis. (AP Photo/St. Louis Post-Dispatch, Chris Lee) EDWARDSVILLE INTELLIGENCER OUT; THE ALTON TELEGRAPH OUT.

St. Louis Cardinals starting pitcher Chris Carpenter throws during the first inning of a baseball game against the Cincinnati Reds, Tuesday, Oct. 2, 2012, in St. Louis. (AP Photo/Jeff Roberson)

Detroit Tigers' Miguel Cabrera watches his single off Kansas City Royals starting pitcher Jeremy Guthrie during the first inning of a baseball game at Kauffman Stadium in Kansas City, Mo., Tuesday, Oct. 2, 2012. (AP Photo/Orlin Wagner)

Oakland Athletics' Grant Balfour reacts as the final out is made against the Texas Rangers at the end of a baseball game Tuesday, Oct. 2, 2012, in Oakland, Calif. The A's won 3-1.(AP Photo/Ben Margot)

New York Yankees' Raul Ibanez celebrates his ninth inning, two-run home run with Robinson Cano against the Boston Red Sox during their baseball game, Tuesday, Oct. 2, 2012, in New York. The Yankees won 4-3 in the 12th inning. (AP Photo/The Record of Bergen County, Tyson Trish) MAGS OUT; TV OUT; INTERNET OUT; NO ARCHIVING; MANDATORY CREDIT

ST. LOUIS (AP) ? Rather than spraying champagne in every direction, the defending World Series champions talked about holding a subdued party if they squeezed into the postseason.

When it finally happened, the St. Louis Cardinals just couldn't help themselves.

First-year manager Mike Matheny, wearing a uniform top over an undershirt that was soaked and aromatic from the bubbly that flowed, addressed the media outside the clubhouse around 1 a.m. local time after the Cardinals clinched the second NL wild card when Los Angeles lost to San Francisco.

The Dodgers' elimination set up a final hectic day to the regular season in which the AL West and AL East crowns are up for grabs, and Miguel Cabrera can become baseball's first Triple Crown winner since Carl Yastrzemski in 1967.

Just before Matheny emerged, raucous cheering could be heard.

"I think they realized how special this is," Matheny said. "You can't take these for granted. We were talking about it being kind of subdued and it was, but they're still proud. And had every right to be."

Nobody seemed to mind too much that they backed in, earning a one-game playoff Friday against the Braves in Atlanta.

"We were the last one in, but we have an opportunity to do something special," said pitcher Chris Carpenter, the loser in a 3-1 setback to the Cincinnati Reds Tuesday night. "I think the way the ballclub's playing right now we have a chance to move on.

"Hopefully, we can come out and do the things we've been doing for the last two or three weeks."

While all 10 playoff spots in the majors are taken, the Cardinals-Braves game is the only pairing that's set.

For the second season in a row, a hectic scramble is shaping up with first place and home-field advantage at stake.

Oakland, Texas, Baltimore and the New York Yankees can all take division titles. Each club is already assured a postseason slot.

Texas plays at Oakland in the afternoon ? they're tied and the winner earns the West title, the loser gets a wild card.

"No one said it was going to be easy," Rangers manager Ron Washington said. "We started out to play 162 games and now ? tomorrow ? it's 162. And we'll see what happens."

In the East, the Yankees can win it at home if they beat Boston or if second-place Baltimore loses at Tampa Bay. If the Orioles overcome their one-game deficit Wednesday night, they'll host the Yankees in a tiebreaker Thursday.

"We have the chance to have the best record, and that's the bottom line and that's a good feeling that you can control that," Yankees manager Joe Girardi said.

Washington, Cincinnati and San Francisco won their NL divisions. Detroit has wrapped up the AL Central, and Cabrera is in position to win the Triple Crown.

Cabrera has 44 home runs, one more than Texas' Josh Hamilton. The Tigers star is hitting .331, seven points ahead of Angels rookie Mike Trout, and his 139 RBIs are 11 more than Hamilton's total.

Cabrera has deflected attention of his achievement to his team's success. There will be time to celebrate ? in the meantime, there are still two divisions to be decided.

Shades of last year, sort of, when the Cardinals and Tampa Bay claimed wild-card spots on a thrilling final day, chasing the Braves and Boston from the postseason picture.

This time, the races are all about seeding. Division winners can avoid a dangerous all-or-nothing game for the wild card, something baseball added this year.

The Cardinals are aiming to duplicate their success last fall, when they parlayed a wild-card berth into the franchise's 11th title, beating the Phillies, Brewers and Rangers to give manager Tony La Russa a fitting send-off.

No one seemed to mind that this year they'll have to be clicking from Day 1 ? or it'll be over.

"A lot of clubs were in it at the end and it worked out for us," team chairman Bill DeWitt Jr. said. "We need to go down there and win. We have the talent to go as far as our fortunes take us."

Matheny named 16-game winner Kyle Lohse as the starter Friday against the Braves. He also could have gone with Adam Wainwright, bumped from the start in the regular-season finale Wednesday to save his arm for the postseason.

"What is there not to like about him? I mean, what more can he do?" Matheny said of Lohse. "It's kind of lined up that way and we've had that in line for a while."

Lohse got a strong endorsement from Carpenter, who was 4-0 in the postseason last fall including must-have wins over Phillies ace Roy Halladay in Game 5 of the NL Division Series and Game 7 over the Rangers.

"There's no doubt about it, he's been our most consistent guy all year," Carpenter said. "I don't think it's been said enough because they might not think he's an exciting guy ? he doesn't throw 95 miles an hour, doesn't strike out 250 guys a year ? but when he's been healthy he's been one of our best pitchers.

"He deserves this game, he deserves to go out there and take it on."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2012-10-03-Playoffs%20Rdp/id-e3194dc3ac42446b8a00ee7618b344cb

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Study finds faults in proposed mental disorder diagnosis

ScienceDaily (Oct. 3, 2012) ? A much anticipated addition to the revised Diagnostic and Statistical Manual of Mental Disorders fifth edition (DSM-5) is questionable according to research findings. The newly revised DSM-5, the first alterations since it was last revised in 1994, includes attenuated psychosis syndrome (APS), a new diagnosis that would identify those impaired by preliminary psychotic symptoms that do not meet the threshold for an existing diagnosis as having a psychotic disorder. In an effort to understand the impact this new diagnosis would have in a real clinical setting, researchers at Butler Hospital, Brown University and Rhode Island Hospital studied how APS applied in an outpatient clinic, and found reasons for concern.

The findings are published in the October issue of Journal of Clinical Psychology.

Published by the American Psychiatric Association, the DSM provides standard criteria for the diagnosis of mental disorders and is used by clinicians and other key mental healthcare professionals across the U.S. "Including APS as a new diagnosis in the DSM-5 has been an issue of debate since its first consideration because of the negative impact it could have on patients and their families," said Brandon Gaudiano, PhD, a research psychologist at Butler Hospital and an Assistant Professor of Psychiatry & Human Behavior at the Alpert Medical School of Brown University. One of the original rationales for APS was to help identify patients who are at high risk for transition to a psychotic disorder in the near future but do not currently meet the criteria for one of the existing DSM-4 psychotic disorder diagnoses. In the study of over 1,200 patients, the researchers did not identify a single patient who met the criteria for APS who did not already meet the criteria for another existing DSM disorder, thus calling into question the true need for the new diagnosis.

The study also found that 28 percent of clinic patients reported these attenuated psychotic symptoms in addition to their other common psychiatric symptoms. The researchers believe that these attenuated symptoms are better explained by the patients' existing conditions, such as depression and anxiety in most cases, and are unlikely to represent true psychotic symptoms. However, if included in the new DSM-5, the fear is that many clinicians could simply give APS as an additional diagnosis, thus causing many more patients to be inappropriately labeled as potentially "psychotic."

"APS has been a controversial topic because the introduction of this diagnosis would basically lower the threshold for diagnosing someone with a psychotic-type disorder. Making such a diagnosis has serious implications because it could lead to inappropriate treatments such as antipsychotic medications that could pose more risks than benefits for these patients or increased stigma," said Gaudiano.

Researchers and clinicians anticipate APS to be included in the appendix of the revised DSM-5 coming out in 2013, not the main text. As Gaudiano explains, this would not officially recognize the syndrome as an accepted diagnosis, but rather open the door for discussion of its utility and allow for further studies of if and how APS may be made more useful and less problematic.

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The above story is reprinted from materials provided by Women & Infants Hospital, via EurekAlert!, a service of AAAS.

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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/mind_brain/depression/~3/G6K7VX5zeWI/121003111357.htm

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French First Lady: My tweet was a 'mistake'

PARIS (AP) ? France's first lady says in an interview published Wednesday that she regrets posting on Twitter a comment that many French read as a not-so-veiled dig against the mother of President Francois Hollande's four children.

Nearly four months after causing the stir now dubbed "Tweetgate" in France, Valerie Trierweiler told regional newspaper Ouest-France that her comment on Twitter was a "mistake" and she's learned from it.

During France's legislative elections in June, Trierweiler sent tongues wagging by tweeting words of encouragement to a dissident Socialist who was running against Segolene Royal ? Hollande's former partner. Royal was vying to represent a region in western France, and ended up losing.

Trierweiler, a professional journalist who once hosted her own cable TV show, admitted that she had been clumsy, and hadn't yet realized that after Hollande took office in May she was "no more just a simple citizen."

"It won't happen again," she was quoted as saying of the tweet.

Trierweiler took the comment off her Twitter account weeks ago, but the fallout lives on: A leading satirical TV show continues to parody the alleged rivalry between Trierweiler and Royal, with Hollande depicted as uncomfortable ? and essentially powerless to stop it ? in the middle.

A new poll released Wednesday suggests that most French don't have a positive opinion of Trierweiler. Hollande's popularity, meanwhile, has been sliding in recent months ? although that's likely due to a variety of factors including a sluggish French economy and high joblessness.

Asked whether her fellow journalists had been unfair over the tweet, Trierweiler told Ouest-France: "The handling (of it) especially seemed out of proportion to me."

The twice-divorced mother of three says she's now getting a better grasp of her role as first lady. For example, she said in the interview that she had decided not to take up a new "humanitarian-minded" TV project that drew recent media reports.

"I understand that, for some people, being the president's partner and working for a television station could raise questions, even cause problems," she said.

Trierweiler recently took up a role with the humanitarian foundation founded by Danielle Mitterrand, the late wife of former President Francois Mitterrand ? France's only other postwar Socialist head of state aside from Hollande.

"Being at the side of the president requires me to look at things differently, to have concerns that are less personal," Trierweiler said.

Source: http://news.yahoo.com/french-first-lady-tweet-mistake-161502315.html

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